Anti-Cancer Influence Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Breast Cancer

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Anti-Cancer Influence Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Breast Cancer




Xao tam phan (Paramignya trimera (Oliv.) Guillaum) can be a Vietnamese traditionally medicinal plant utilized in treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This research aimed to investigate the effects of 5 various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the best antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (with the exception of total flavonoids) and antioxidant capacity, when compared to conventional and ultrasound-assisted extractions. These data reveal that the use of methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application in the nutraceutical and/or pharmaceutical industries.




Drying methods, solvents and extraction methods greatly modify the phytochemical compounds and biological activity from plant materials. The aims with this study would determine the end results of various drying methods, various solvents and extraction methods about the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root purchased from Vietnam. The outcome established that microwave drying was an efficient method in eliminating water when it comes to shortest drying time, lowest energy consumption as well as retention of phytochemical compounds and antioxidant capacity in the P. trimera root while methanol and microwave-assisted extraction were the top solvent and method for greatest extraction with the phytochemical compounds and antioxidant capacity from your P. trimera root. The findings from this study allow retaining the very best numbers of phytochemical compounds and antioxidant capacity through the P. trimera root for potential application in the nutraceutical industry.


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